FANTASTIC FOUR (1961) #110

It had to happen. The FF couldn’t go on forever. If you read no other comic this month, you must not miss « One From Four Leaves Three! » Featuring plenty of witchcraft! Reed has lost the device to bring him back from the Negative Zone, and it is up to the remaining three to get it to him so he can escape Annihilus! With the help of some magical diversion, Reed is able to slip past the Lord of the Negative Zone. The Change in attitude that had begun showing signs earlier in Ben are now coming to the forefront; he has changed into a belligerent, arrogant person, and the group soon finds Ben has left the team to strike out on his own!