FANTASTIC FOUR (1961) #111

The rampaging Thing turns the city of New York into a blazing battleground, as he attacks the Torch and Mr. Fantastic. And then- enter Bruce Banner! A Deranged Thing slugs it out in the streets of New York against the Human Torch, destroying everything in its wake! Reed calls in Bruce Banner to help him create an antidote to the Thing’s condition, but naturally when Banner arrives and sees the Thing, he gets excitable and the next thing you know, the Thing and the Hulk are about to face-off!