AMAZING SPIDER-MAN (1963) #420

This Christmas issue leads Spiderman to reflect on the losses of his Aunt May and the loss of his child in the delivery room with his wife, Mary Jane. On setting to a Daily Bugle mission to report of a mutant psychic in Central Park, Spiderman gains unlikely counseling by an extra-dimensional mutant known as Nate Grey a.k.a. X-Man.