FANTASTIC FOUR (1961) #182

Counter-Earth Reed traps Johnny and Ben in the Negative Zone! Plus, it’s more than a lover’s quarrel when Sue confirms that this evil Reed has no regard for their son! Enter: The Mad Thinker! The Brute, aka Reed Richards from Counter-Earth, sends the Human Torch and the Thing into the Negative Zone, from where he expects they will never return. Then some mysterious beings kidnap Agatha Harkness and little Franklin Richards, much to the shock of the Invisible Girl, who arrives at Whisper Hill just as they are vanishing. Back in the Negative Zone, the Torch and the Thing are stunned to see Reed with Annihilus and some giant creature.… Notes : Features the Hostess Cup Cakes ad, Captain America And The Sore Sir’s Apprentices