SPECTACULAR SPIDER-MAN (1976) #221

Spiderman has succumbed to a crippling disease after combatting Stunner and lays near death at the mercy of Dr. Octopus of his laboratory. In town, Kaine hunts down Spiderman’s enemies, Mary Jane Parker reflects on motherhood with Spiderman’s dangerous lifestyle, and a death occurs in Spiderman’s life- but not who you’d expect.