SPECTACULAR SPIDER-MAN (1976) #239

Inside his Florida laboratory, Dr. Curt Connors changes into the Lizard and saves his family! That’s wonderful! So now after defeating the reptile beast, the Lizard will change back…right? Uh-oh, no he won’t! Because the Lizard has plans to rule the world with his slimy friends by his side! Quickly realizing the imminent danger to Martha and Billy, the web-slinger (aka Ben Reilly) tosses the Lizard out into the swamp! Is this where the Sensational Spider-Man will make his last stand vs. the Lethal Lizard? Yesss! Cameo appearances by Peter Parker and Mary Jane Watson. (Notes: The Lizard returns in Spider-Man Unlimited 19. This issue was reprinted in 2012 in the trade paperback: Amazing Spider-Man The Complete Ben Reilly Epic #5.)